Proteolytic enzymes, including bromelain, papain and
protease, are enzymes that specifically act on protein.
Protease taken with food is completely dedicated to
the digestive process and breaks down dietary proteins
into smaller peptides and amino acids that can be easily
absorbed. When taken on an empty stomach with no food
to digest, protease can be absorbed intact into the
bloodstream where it appears to help restore and maintain
healthy
It is well documented that protease acts differently
in the tissues of the body than it does in the digestive
tract.
Both
clinical and laboratory research shows that
proteolytic enzymes taken on an empty stomach
can have a beneficial effect on the immune
system and inflammatory processes. In addition,
the amount of protease needed for systemic
activity is often much greater than that
needed for digestion. Yet most systemic
protease products on the market contain
the same protease blend found in digestive
products. Laboratory analyses have also
found that certain protease exhibits considerably
greater activity in the blood than other
protease.
The
significance of alpha-2-macroglobulins
These
macroproteins exist in large numbers
in the presence of inflammation. They
help deliver cytokines, macrophages
and fibroblasts to the site of inflammation,
so they can begin the work of repairing
damaged tissue.
Once in the bloodstream, specific protease
binds to alpha-2-macroglobulins, causing
them to shift to their activated form, which
increases their mobility. This recently
patented mechanism for increasing activated
alpha-2-macroglobulin in the blood and extravascular
tissue (US patent 6,413,512) emphasizes
the importance of using systemic protease
products that function in the physiological
conditions of the blood and tissues
pHysioProtease
is a proprietary blend of proteases available
exclusively in select products distributed
by Enzymes, Inc. Research has shown that
pHysio-Protease has the precise combination
of proteases for optimal activity in the
physiological conditions of the blood and
other tissues providing maximum patented
systemic action. Calcium is added to help
prevent the depletion of intracellular calcium
that may result from the presence of this
highly active blend of proteases in the
blood.
A recent study compared pHysioProtease with
three commercially available protease blends
recommended for systemic use. The results
revealed that pHysioProtease provided significantly
more systemic enzyme activity per dose.
*pHysio-U
is our designation for the proteolytic
activity expected in the tissues. This
unit is based on an innovative assay
developed to measure the activity of
protease in simulated conditions for
the temperature, pH, substrates and
buffering mechanisms of the blood. The
FCC HUT designation is an indicator
of the proteolytic activity in the conditions
of the digestive tract, not
the body tissues.
InflammEnz
is beneficial for use with soft-tissue trauma
and
post-operative protocols.
These
statements have not been evaluated by the Food and Drug Administration.
The products listed are not intended to diagnose, treat, mitigate, cure
or prevent any disease.